The growth modulation of somatostatin on human pancreas carcinoma cell lines HS 766T
- VernacularTitle:生长抑素对人胰腺癌细胞株HS766T的生长调控
- Author:
Min ZHAO
;
Qing JIA
;
Ruolan JIANG
- Publication Type:Journal Article
- Keywords:
Pancreatic neoplasms;
Somatostatin
- From:
Chinese Journal of General Surgery
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the growth inhibition of somatostatin (SS) on human pancreas carcinoma cell strains HS766T and its mechanism.MethodsHS766T cells cultured in DMEM medium containing 10% FCS were treated with SS.Proliferation and viability of cell was measured by the Mosmann′s method (MTT). Intracellular adenosine monophosphate levels was detected by radioimmunoassay. Intracellular Ca 2+ level were measured using a F-2000 flurorescence spectrophotometer.ResultsSS inhibited the proliferation of HS766T in a concentration dependent manner (P