Pharmacodynamics and Clinical Therapeutic Effect of Jiakang Ⅰ Oral Liquid
- VernacularTitle:甲康Ⅰ号口服液药效学及临床疗效观察
- Author:
Yi ZHENG
;
Wanchun CAI
;
Lifu JIANG
;
Jiatao ZHAI
;
Wei YAO
;
Yaping MA
- Publication Type:Journal Article
- Keywords:
Jiakang I oral liquid;
pharmacodynamics;
clinical therapeutic effect
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the pharmacodynamics and therapeutic effect of Jiakang Ⅰ oral liquid.METHODS:The drug actions of tapazole,NS and Jiakang Ⅰ were compared in the animal model of hyperthyroidism.205 hyperthyroidism cases were treated with Jiakang Ⅰ in a double blind design and the therapeutic effect was observed.RESULTS:Pharmacodynamic observation revealed that Jiakang Ⅰ could decreased T3,T4 and increase TSH significantly in rats.Compared with control group treated with tapazole or NS,in Jiakang Ⅰ group,T3 and T4 were obviously reduced and TSH was increased and the clinical symptoms were alleviated without any marked adverse reaction.CONCLUSION:The hyperthyroidism animal model can be applied to evaluating the pharmacodynamic effect of Jiakang Ⅰ.This drug has satisfactory therapeutic effect on hyperthyroidism.
