Determination of the Contents of Components in Co-ciprofloxacin Injection by RP-HPLC
- VernacularTitle:反相高效液相色谱法测定复方环丙沙星注射液的含量
- Author:
Aimin CHEN
;
Mingran JING
- Publication Type:Journal Article
- Keywords:
RP-HPLC;
ciprofloxacin;
tinidazole;
compound ciprofloxacin injection
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To determine the contents of ciprofloxacin and tinidazole in compound ciprofloxacin injection.MET_HODS:RP-HPLC method has been developed.The moble phase was 0.4mol/L citric acid-methanol-acetonitrile(2∶1∶0.8).The flow rate was 0.8ml/min.The detective wavelength was 277nm.RESULTS:The average recovery and relative stan_dard deviation were 99.7% and 0.9% for ciprofloxacin,99.6% and 0.7% for tinidazole.CONCLUSION:This method is rapid,simple,accurate and suitable for the quality control of this preparation.
