Intravenous Immune Globulin Therapy For 14 Cases of Rh Hemolytic Disease of Newborn
- VernacularTitle:静脉注射丙种球蛋白治疗14例新生儿Rh溶血病的临床观察
- Author:
Huixin WANG
;
Mingchang WU
;
Caiyun YANG
- Publication Type:Journal Article
- Keywords:
Immuneo globulins, intravenous;
Erythroblastosis, fetal;
Rh-Hr blood-group system
- From:
Chinese Journal of Perinatal Medicine
1998;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of intravenous immune globulin (IVIG) therapy on newborn infants of Rh hemolytic disease. Methods IVIG group (n=14) received conventional treatments including albumin administration and phototherapy with additional IVIG therapy at a daily dose of 400 mg/kg given for 1～5 consecutive days,and control group (n=16) only received conventional treatments. Effects were compared between the two groups. Result There were 25 patients with hyperbilirubinemia caused by Rh hemolytic disease received exchange transfusions. IVIG was infused in 12 cases,100% of them had the total serum bilirubin level dropped down during the treatment before the exchange transfusions, vs 5 (38%) of 13 cases in control group (P
