Experimental study on calculous cholecystitis before and after cholecystolithotomy
- VernacularTitle:结石性胆囊炎取石前后胆囊炎症变化的实验研究
- Author:
Zhuori LI
;
Zhijiang WANG
;
Xieqi WU
- Publication Type:Journal Article
- Keywords:
CHOLELITHIASIS/etiol;
RECURRENCE;
CHOLECYSTITIS/pathol;
GALLBLADDER/pathol;
DISEASE MODELS,ANIMAL
- From:
Chinese Journal of General Surgery
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the pathologic changes of the gallbladder in rabbits with calculous cholecystitis and the causes of gallstone recurrence after choleystolithotomy. Methods Twenty- four rabbits were randomly divided into four groups:(1) normal control group (n=5);(2) operative control group(n=5);(3) stone-implanted(S-I) group (n=6),and (4)stone- removed(S-R) group(n=8).The human cholesterol gallstones were implanted into the rabbit gallbladder in stone-implanted and stone- removed rabbits,The pathologic change of the gallbladder was observed by light microscopy 3 months before and after cholecystolithotomy. Results (1)The wet weight of gallbladder in the S-R group [ (1.1?0.06)g] was significant higher than that in S-I group [(0.515?0.1)g] (P0.05);(3)Sever chronic cholecystitis was 33.3% in S-I group 87.5% and in S-R group(P
