Relationship between expression of CD44v6 and matrix metalloproteinase-2 and the invasion and matastasis of gallbladder carcinoma
- VernacularTitle:CD44v6和基质金属蛋白酶-2表达与胆囊癌的侵袭和转移关系
- Author:
Yue HAN
;
Jingsen SHI
;
Yijun YANG
;
Jiansheng WANG
;
Aijun ZHU
;
Guocai LI
- Publication Type:Journal Article
- Keywords:
GALLBLADDER NEOPLASMS/pathol;
ADENOCARCINOMA/pathol;
NEODLASMS METASTASIS;
GALLBLADDER NEOPLASMS/genet;
ADENOCARCINOMA/genet;
CD44v6;
MMP-2
- From:
Chinese Journal of General Surgery
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the role of CD44v6 and matrix metalloproteinase-2(MMP-2) in the invasion and metastasis of gallbladder carcinoma (GC). Methods Immunohistochemical techniques were adopted to detect the expression of CD44v6 and MMP-2 in 42 cases of GC and 10 cases of cholecystolithiasis. Results (1)The expression of CD44v6 in the GC group (64.3%, 27/42) was significantly higher than that in the cholecystolithiasis group (0%,0/10). The expression of CD44v6 was correlated with GC histologic grade (P
