Effects of lipopolysaccharide on proliferating cell nuclear antigen expression on alveolar macrophages and Fas/FasL system expression on alveolar type Ⅱ epithelial cells in smoking rats
- VernacularTitle:脂多糖对吸烟大鼠肺泡巨噬细胞增殖细胞核抗原及肺泡Ⅱ型上皮细胞Fas/FasL系统表达的影响
- Author:
Juan FU
;
Yongjian XU
;
Zhenxiang ZHANG
- Publication Type:Journal Article
- Keywords:
Smoking;
Antigens;
Lipopolysaccharides
- From:
Chinese Journal of Pathophysiology
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the effect of proliferating cell nuclear antigen (PCNA) expression on alveolar macrophages (AM) and Fas/FasL expression on alveolar type Ⅱ epithelial cells induced by lipopolysaccharide (LPS) in smoking rats. METHODS: Immunohistochemistry SABC and immunofluorescence techniques were used to examine PCNA expression on AM and Fas/FasL system expression on alveolar type Ⅱ epithelial cells in smoking rats of different stages induced by LPS. RESULTS: The AM PCNA expression in smoking rats reached the highest level after 3 or 4 months. The AM PCNA expression in every groups stimulated by LPS significantly increased ( P
