Detection of carcinoembryonic antigen in distal mesorectum in 26 patients with rectal cancer
- VernacularTitle:直肠癌患者远端直肠系膜癌胚抗原检测及临床意义
- Author:
Guole LIN
;
Huizhong QIU
;
Ting LIU
- Publication Type:Journal Article
- Keywords:
Rectal neoplasms;
Mesentery;
Carcinoembryonic antigen
- From:
Chinese Journal of General Surgery
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo evaluate the reasonableness of total mesorectal excision (TME) in the management of rectal cancer. Methods The carcinoembryonic antigen (CEA) level of surgically removed distal mesorectum (3?cm below the tumor),tumor tissue and normal mesocolon was detected by microparticle enzyme immunoassay in 26 rectal cancer patients. Results The CEA level in normal mesocolon was (1.6?1.0)?ng/g, and (62.5?85.2)?ng/g in distal mesorectum(P1?000?ng/g).ConclusionsIn patients with rectal cancer, much higher CEA level in distal mesorectum than in normal mesocolon might indicate distal mesorectal dissemination. It is necessary to routinely perform TME in the surgical management of middle and lower rectal cancer.
