Preparation and Clinical Application of Rufloxacin Eye Drops
- VernacularTitle:芦氟沙星滴眼液的研制及临床应用
- Author:
Xintian LI
;
Xiangyang WANG
;
Lianqiang ZHANG
- Publication Type:Journal Article
- Keywords:
rufloxacin;
eye drops;
quality control;
clinical use
- From:
China Pharmacy
1991;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To prepare rufloxacin eye drops METHODS:The content of rufloxacin was determined with HPLC method The therapeutic effect of the eye drops was observed in 150 out-patients with severe ocular infections RESULTS:Determined by HPLC method,the average recovery of rufloxacin was 100 12%(RSD=1 18%) After treatment,130 patients recovered,16 improved and had no efficiency with a total effective rate of 97 33% CONCLUSION:The eye drops have definite therapeutic effect The HPLC method is simple,rapid and accurate in determination of the content and no special reagent is needed
