The Expression of TGF-?_1 And Its Significance in Human Gastric Cancer
- VernacularTitle:TGF-?_1在胃癌中表达及意义
- Author:
Zhenyu ZHANG
;
Jiang CHEN
;
Chaomei KON
- Publication Type:Journal Article
- Keywords:
Gastric cancer;
Tumor;
Growth,factor;
Immunohistochemistry
- From:
Journal of Chinese Physician
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the role TGF-? 1 expression in the gastric cancer and to evaluate its clinical and pathological significance.Methods The expression of TGF-? 1 was studied by using S-P immunohistochemical technique in 20 cases of normal gastric tissue and 46 cases of gastric carcinoma.Results in the gastric cancer patients,the positive rate of TGF-? 1 expression was 100%,but there was 50% positive rate in the normal gastric tissues.The TGF-? 1 expression in group with lymph node metastasis was higher than that without lymph node metastasis.Conclusion TGF-? 1 plays an important role in the progress of gastric cancer.