Clinical Characteristics of Renal Cell Carcinoma in Dialysis Patients.
- Author:
Young Ok KIM
1
;
Chang Hee HAN
;
Ok Ran SHIN
;
Jung Min YOON
;
Seok Joon SHIN
;
Yoon Kyung CHANG
;
Sun Ae YOON
;
Chul Woo YANG
;
Dong Chan JIN
;
Yong Soo KIM
;
Suk Young KIM
;
Yoon Sik CHANG
;
Byung Kee BANG
Author Information
1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. drsykim@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Chronic renal failure;
Dialysis;
Renal cell carcinoma
- MeSH:
Carcinoma, Renal Cell*;
Classification;
Diagnosis;
Dialysis*;
Flank Pain;
Follow-Up Studies;
Glomerulonephritis;
Humans;
Incidence;
Kidney Failure, Chronic;
Korea;
Medical Records;
Nephrectomy;
Peritoneal Dialysis;
Polycystic Kidney, Autosomal Dominant;
Prognosis;
Recurrence;
Renal Dialysis;
Retrospective Studies;
Rupture
- From:Korean Journal of Nephrology
2003;22(5):559-564
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The incidence of renal cell carcinoma (RCC) in patients receiving long-term hemodialysis or peritoneal dialysis patients is 100-fold higher than that in general population. But the clinical study about RCC in dialysis patients is not reported in Korea yet. This study was performed to evaluate the clinical characteristics of RCC in dialysis patients. METHODS: We retrospectively investigated medical records of dialysis patients who were diagnosed with RCC between patients January, 1993 and December, 2002. RCC diagnosed before first dialysis was excluded. Diagnosis of RCC was made by both radiologic and pathologic examinations. RESULTS: A total of 7 patients was diagnosed with RCC. Mean age was 46+/-9 years. Primary renal disease consisted of chronic glomerulonephritis (n=3), autosomal dominant polycystic kidney disease (n=3), and hypertensive nephropathy (n=1). Five patients were on hemodialysis, 2 were on peritoneal dialysis. Mean duration of dialysis was 82+/-46 months. The presenting symptoms were asymptomatic in 2 patients, sudden onset of flank pain due to spontaneous renal cyst rupture in 3, palpable abdominal mass in 2. Mean tumor size was 3.1+/-1.9 cm and multiple renal cysts were noted in all patients. According to the TNM classification for RCC, 6 patients had stage I and 1 patients had stage IV. Six patients with stage I were treated with nephrectomy. With a mean follow-up of 45+/-35 months after the operation, there has been no recurrence. CONCLUSION: Six patients out of total 7 patients had early stage tumor and all these patients were treated with nephrectomy and the prognosis was good. All RCC were associated with inherited or acquired multiple renal cysts.
