Preparation and Clinical Application of Ribavirin and Ephedrine Nasal Spray
- VernacularTitle:利麻鼻用喷雾剂的制备及临床应用
- Author:
Yong LIANG
- Publication Type:Journal Article
- Keywords:
ribavirin and ephedrine nasal spray;
preparation;
quality control;
clinical application
- From:
China Pharmacy
1991;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the preparation and quality control methods of ribavirin and ephedrine nasal spray and observe its clinical therapeutic efficacy.METHODS:To determine the content of ribavirin and that of ephedrine hydrochloride by ultraviolet spectrophotometry and polarimetry respectively and observe the clinical therapeutic efficacy in 40 patients.RES_ULTS:The average recoveries of ribavirin and ephedrine hydrochloride were 100.05%(RSD=0.50%) and 100.10%(RSD=0.29%) respectively.Its effective rate in treating virus infections of upper respiratory tract was 97%.CONCLUSION:The preparation of ribavirin and ephedrine nasal sprays is reasonable in technology,stable in quality,feasible in quality control and reliable in therapeutic efficacy.It is worth popularizing the application of this preparation.
