Comprison of the Cost-effectiveness Between Granisetron and Ondansetron in Preventing Nausea and Vomiting Caused by Cancer Chemotherapy
- VernacularTitle:格拉司琼与恩丹西酮预防化疗后恶心、呕吐的成本-效果分析
- Author:
Jun PANG
;
Fei LI
;
Binghui YANG
- Publication Type:Journal Article
- Keywords:
granisetron;
ondansetron;
chemotherapy;
cost-effectiveness analysis
- From:
China Pharmacy
1991;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To compare the therapeutic effect,adversere reactions and cost-effectiveness between granisetron and ondansetron in preventing nausea and vomiting caused by cancer chemotherapy.METHODS:Using pharmacoeconomic co_st-effectiveness analysis,the relevant therapeutic indices were evaluated.RESULTS:The effective rates of granisetron in preventing nausea and vomiting were 83.6% and 86.8% with an average cost of 210.48 yuans in a therapeutic couse,the cost-ef_fective ratio being 251.77 and 242.37,and those of ondansetron were 72.9% and 83.7% with an average cost of 381.35 yuans,the cost-effective ratio being 523.11 and 456.62.CONCLUSION:Granisetron can effectively prevent nausea and vomiting caused by cancer chemotherapy,and its cost-effective ratio is superior to that of ondansetron.
