Determination of the Content of Ciprofloxacin Lactate in Eye Drops by Dual-wavelength Spectrophotometry
- VernacularTitle:双波长法测定乳酸环丙沙星滴眼液的含量
- Author:
Zhiling YANG
;
Xiaobing DENG
- Publication Type:Journal Article
- Keywords:
dual-wavelength spectrophotometry;
ciprofloxacin lactate;
ethylparaben;
eye drops
- From:
China Pharmacy
1991;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:Dual-wavelength spectrophotometry was developed for the determination of ciprofloxacin lactate in its eye drops.METHODS:Detection was performed at wavelength 237nm and 279nm with 0.1mol/L HCl as diluent.RESU_LTS:The assay was linear for ciprofloxacin lactate in the concentration range of 3～9?g/ml,r=0.9 998;The mean recovery was 101.6%,RSD was 2.16%.CONCLUSION:This method is simple,quick,accurate and suitable for the determination of ciprofloxacin lactate in its eye drops.
