Adenylate Content of Brain Edema Tissue After Trauma
- VernacularTitle:创伤后脑水肿组织腺苷酸含量变化
- Author:
Xiaoju WANG
;
Hansheng JI
;
Zhengang TANG
- Publication Type:Journal Article
- Keywords:
Brain,edema;
Trauma;
Adenylate;
High Performance liquid chromatography
- From:
Journal of Chinese Physician
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objection To explore adenylate content of traumatic brain edema tissue and the relationship between ad-enylate content and brain edema.Methods The 20 rabbits with traumatic brain edema were sacrificed by decapitation in different periods,other 4 rabbits brain as control group.The brain tissue in the ringed traumatic site was used to measure brain water content and adenylate including AMP,ADP and ATP contents with HPLC.Results The adenylate content of traumatic brain edema tissue was lower than that of normal brain tissue,and further obviously reduction with longitude after trauma,and consistent with brain edema extent.Condusion The adenylate content of traumatic brain tissue is reduced along with brain edema severity and there is obviously correlation.