Detection of Human Herpesvirus 8 in Kaposi′s Sarcoma by Fluorescence in situ Polymerase Chain Reaction in Xinjiang
- VernacularTitle:新疆Kaposi肉瘤组织内人类8型疱疹病毒DNA的检测
- Author:
Xiaojing KANG
;
Dawei SHEN
;
Xiongming PU
- Publication Type:Journal Article
- Keywords:
Sarcoma,Kaposi;
Herpesvirus,Kaposi sarcoma associated;
Fluorescence in situ polymerase chain reaction
- From:
Chinese Journal of Dermatology
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the localization of human herpesvirus (HHV-8) in lesions of Kaposi′s Sarcoma (KS) and explore the role of HHV-8 in the pathogenesis of KS in Xinjiang. Methods HHV-8 DNA was detected by fluorescence in situ polymerase chain reaction. A total of 40 paraffin-embeded specimens were studied, including 20 KS lesions (12 nodular, 6 plaque and 2 patch lesions) and 20 non-KS lesions (18 dermatofibroma and 2 hemangioma). Results HHV-8 DNA was detected in 17 (85%) of 20 KS lesions and none in non-KS lesions (P
