Serum Interleukin-6, Interleukin-8 and Tumor Necrosis Factor-? in Secondary Syphilis
- VernacularTitle:二期梅毒患者血清白介素6、白介素8及肿瘤坏死因子?测定
- Author:
Shuanglin CAO
;
Lingling FU
;
Mei FU
- Publication Type:Journal Article
- Keywords:
Syphilis;
Interleukin 6;
Interleukin 8;
Tumor necrosis factor
- From:
Chinese Journal of Dermatology
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of interleukin-6(IL-6), interleukin-8(IL-8) and tumor necrosis factor-?(TNF-?) in the pathogenesis of secondary syphilis, and their relationship with RPR titers and clinical manifestations in secondary syphilis. Methods The serum IL-6, IL-8 and TNF-? were tested by ELISA. RPR titers of the patients were determined simultaneously. Histopathology was performed if skin lesions were present. Results Thirty three cases of secondary syphilis were studied. The average levels of serum IL-6, IL-8 and TNF-? were 78.7?82.5 pg/mL, 171.9?117.9 pg/mL and 115.7?67.9 pg/mL, respectively, in syphilis group, which were significantly higher in comparison with those in controls (P
