Study on the Relationship Between the Levels of IL-4 and Total Serum IgE in Patients with Seasonal Contact Dermatitis
- VernacularTitle:季节性接触性皮炎患者白介素4水平与血清总IgE含量的关系
- Author:
Yanqun LIU
;
Jing HE
- Publication Type:Journal Article
- Keywords:
Dermatitis,contact;
Interleukin 4;
IGE
- From:
Chinese Journal of Dermatology
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the levels of total serum IgE and IL-4 in patients with seasonal contact dermatitis. Methods Total serum IgE was tested by immunoradiometric assay(IRMA) in 29 cases of seasonal contact dermatitis, 35 cases of allergic contact dermatitis and 24 cases of healthy controls. Production of IL-4 was detected by ELISA from peripheral blood mononuclear cells (PBMC) cultured with PHA for 48 hours. Results The levels of IL-4 secreted by PBMC and total serum IgE were significantly higher in patient with seasonal contact dermatitis than those in control group (P
