One stage resection combined with chemotherapy for the treatment of colorectal cancer with hepatic metastasis
- VernacularTitle:结直肠癌肝转移一期联合手术化疗的临床研究
- Author:
Yi ZHANG
;
Zhiyi FENG
;
Shengjia WANG
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Neoplasms metastosis;
Surgical procedure, operative;
Chemotherapy, adjuvant
- From:
Chinese Journal of General Surgery
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of one stage resection combined with chemotherapy for the treatment of colorectal cancer with hepatic metastasis.Methods In this study 17 out of 36 colorectal cancer patients with hepatic metastasis underwent one stage tumor resection embolization and chemotherapy via hepatic artery and portal vein through pumps in 10 cases. The remaining 19 cases in which metastatic tumors judged as nonresectable received embolization and chemotherapy alcohol injection and electrothermotherapy for the metastatic tumors.Results Recurrence developed in 6 out of 7 patients not receiving primary combined embolization and chemotherapy. The diameter of tumors in the 19 patients decrased by 57% on average, among which 4 patients underwent secondary resection of the metastatic tumors. The 1,2,3 year′s survival rate was 94%, 82%, 65% in combined group, and 74%, 53%, 32%(P
