Screening of Effective Antioxidant in Tretinion Ointment
- VernacularTitle:维A酸软膏中抗氧剂的初步筛选
- Author:
Feng SHAO
;
Yun CHEN
;
Chongpu ZHANG
- Publication Type:Journal Article
- Keywords:
tretinion;
antioxidant;
accelerate test;
HPLC
- From:
China Pharmacy
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To screen the effective antioxidant in tretinion ointment METHODS:The six tretinion ointments were prepared with different antioxidants and the same base Based on the accelerated test design,the tretinion concentration was determined by HPLC RESULTS:The ointment with the antioxidant D exhibited the least oxidation rate CONCLUSION:Data from accelerated test demonstrated that the compound antioxidant D was the best one in this formula