Study on Quality Standard of Bikemin Capsule
- VernacularTitle:必克敏胶囊质量标准的研究
- Author:
Songqing LIU
;
Qing DAI
;
Zhangyang WANG
;
Mei ZHANG
;
Yinglan ZHAO
- Publication Type:Journal Article
- Keywords:
Bikemin capsule;
ephedrine;
pseudoephedrine;
TLC;
HPLC
- From:
China Pharmacy
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish the quality standard of Bikemin capsule to control the quality METHODS:TLC method was used for the identification of Ephedra sinica and the detection of limitation of aconitine in Bikemin capsule Ephedrine and pseudoephedrine in the capsule were determined by HPLC on C18 column with the detection wavelength at 215nm RESULTS:The standard curves of ephedrine and pseudoephedrine were linear in the ranges of 0 02~0 10mg/ml (r=0 9 993) and 0 01~0 05mg/ml(r=0 9 996)respectively The average recoveries were (101 4?1 78)% for ephedrine and (98 08?1 81)% for pseudoephedrine CONCLUSION:The identification method is specific and the determination method is sensitive The quality standard is suitable for control of quality of Bikemin capsule