Study on the Regulatory Effects of Bombesin on the Gastrointestinal Morphology and Proliferation of Mucosa Cells in Neonatal Rabbits
- VernacularTitle:蛙皮素对新生兔胃肠形态及细胞增殖的调节研究
- Author:
Zhenbiao LI
;
Shengmei WU
;
Longhua QIAN
- Publication Type:Journal Article
- Keywords:
Bombesin;
Gastrointestinal system;
Cell division;
Rabbits
- From:
Chinese Journal of Perinatal Medicine
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the regulatory effects of bombesin on the gastrointestinal morphology and proliferation of mucosa cells in neonatal rabbits. Methods Twenty four neonatal rabbits were divided into big,small dose experimental group and control group. The gastrointestinal morphology in neonatal rabbits was observed by using Video Image Digtal Analysis System and electron microscopy, and the proliferative rate of gastrointestinal epithelium cells was detected by using immunohistochemical assay. Results The villous height of duodenum were (520?76),(513?31),(379?44) ?m in three groups respectively. That in experimental group with big or small dose were significantly higher than that in control group( P
