The prophylaxis and treatment of pancreatic infection in severe acute pancreatitis
- VernacularTitle:重症急性胰腺炎胰腺感染的综合性预防及治疗
- Author:
Bin ZHU
;
Jiabang SUN
- Publication Type:Journal Article
- Keywords:
Pancreatitis;
Focal infection;
Combined modality therapy
- From:
Chinese Journal of General Surgery
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the prophyl axis and the timing of operation for pancreatic infection in patients with sever e acute pancreatitis(SAP).Methods 2 23 patients with SAP were treated in ICU from 1990 to 1999. The measures adopted against pancreatic infection included fluid resuscitation, nutritional support, antibiotics and prevention of hypoxemia, hypoperfusion and gut barrier dysf unction etc. Indication for operation in SAP was early pancreatic infection from 1990 to 1994. From 1995 to 1999, drainage of pancreatic abscess or localized infection with debridement of necrotic tissues was adopted. Results 23 (10.3%) patients received operation due t o pancreatic infection. The morbidity rate (8.7%) of pancreatic infection betwe en 1995 to 1999 was lower than that (12.4%) between 1990 to 1994. The postoper ative mortality rate (8%) of pancreatic abscess or localized infection was lower than that (50%) of early pancreatic infection. Co nclusion Comprehensive prophylaxis of pancreatic infection a nd delayed operation for pancreatic abscess or localized infection are effective treatment of SAP.
