Effect of endotoxemia on renal function in patients with obstructive jaundice and intervention by sodium cholate, lactulose, and anisodamine
- VernacularTitle:梗阻性黄疸时内毒素血症对肾功能的影响及胆酸钠、乳果糖和山莨菪碱的干预效应
- Author:
Dezheng XU
;
Mingrong HU
;
Xuegen WANG
- Publication Type:Journal Article
- Keywords:
Cholestasis;
Endotoxemia;
K idney function tests
- From:
Chinese Journal of General Surgery
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the change of perioperati ve endotoxin (ET) level and renal function in obstructive jaundice (OJ) patient and the effect of sodium cholate,lactulose, and anisodamine.Methods Forty-eight OJ patients were randomly divided in to control group(n=15), sodium cholate treatment group(n=11), lactul ose treatment group (n=10) and a anisodamine treatment group(n=12), 21 patients with cholecystolithiasis served as non-jaundiced control group. The levels of plasma ET and endogenous creatinine clearance rate (Ccr) were determi ned in all the cases.Results Compar ed with non-jaundiced control group, plasma ET level increased significantly an d Ccr significantly decreased in OJ group (P
