Expression of vitamin D receptor in rectal carcinoma and mucosa adjacent to carcinoma
- VernacularTitle:直肠癌及其癌旁粘膜中维生素D受体表达的研究
- Author:
Shaohua WANG
;
Weijun TANG
;
Ming ZHONG
- Publication Type:Journal Article
- Keywords:
Rectal neoplasms;
Recptors, ca lcitriol
- From:
Chinese Journal of General Surgery
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the expression of vitamin D receptor (VDR) in rectal cancer and mucosa adjacent to cancer. Methods The VDR expression of tumor tissue,mucos a 2cm apart from tumor and normal mucosa was detected by imunohistochemistry, mi crospectrophotometer and computer image analysis in 21 cases of rectal carcinoma . Results The VDR expression in rec tal tumor (2.4?0.7) significantly decreased compared to that of the norma l mucosa (6.0?0.6)(P