Protein and C_(3b) Fc receptor expression of the macrophage in autotranspla ntated splenictissue
- VernacularTitle:自体移植脾巨噬细胞C_(3b)、Fc受体及蛋白质表达的实验研究
- Author:
Yangjun LAN
;
Weipei CHEN
;
Guangjin GUO
- Publication Type:Journal Article
- Keywords:
Splenosis;
Receptors, compleme nt 3b;
Receptors, Fcxert its inhibitory effect on Tca83 cell line.
- From:
Chinese Journal of General Surgery
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the f un ction of the autotransplanted splenic tissue. Method s 120 Kunming mice were randomly divided into two groups: sham operation group and group of 50% autograft splenic tissue implantation in the om ental pouch after total splenectomy. Six months after, splenic transplants were removed, and C 3b and Fc receptor and the expression of protein on the macr ophages was assayed in the implanted splenic tissue. Results The expression of protein and the receptor on the mac rophage in transplants were similar with that in the normal group. Conclusion The function of the macrophages in t he implanted splenic tissue judged by the expression of protein and receptor is normal, the autotransplanted splenic tissue can fulfil the function of the norma l spleen.
