Preparation of Rapid-disintegrated Lozenge
- VernacularTitle:口腔速崩片的研制
- Author:
Lan CHEN
;
Xinan WU
;
Guorong ZHANG
;
Jianqiao LI
- Publication Type:Journal Article
- Keywords:
rapid-disintegrated lozenge;
excipient;
disintegrating time;
dissolubility
- From:
China Pharmacy
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To prepare a rapid-disintegrated lozenge METHODS:The formula and technology were decided by taking the disintegrating time and dissolubility as standard RESULTS:The lozenge could completely disintegrate in 20s and the accumnlated dissolubility of the model drug was 99% after 5 minutes in phosphate buffer(pH=6 80) CONCLUSION:Using now available equipment,suitable excipients and workmanship can prepare a rapid-disintegrated lozenge
