Changes in cell adhesion molecules and composition of complement activation in patients with acute myocardial infarction
- VernacularTitle:急性心肌梗塞病人细胞粘附分子与补体激活成分的动态变化
- Author:
Chengyu LIU
;
Xinqiang JI
;
Jian YANG
;
Ruiya CUI
- Publication Type:Journal Article
- Keywords:
Coronary artery disease;
Cell adhesion molecules;
Leukocytes;
Complement
- From:
Chinese Journal of Pathophysiology
2000;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To explore the possible changes in cell adhesion molecules and composition of complement activation in patients with acute myocardial infarction (AMI). METHODS: The expression of leukocyte CD18, soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular-cell adhesion molecule-1 (sVCAM-1) and composition of complement activation (sC5b-9) concentrations of patients with AMI (67 cases), old myocardial infarction (OMI, 42 cases) and 38 healthy volunteers were measured using enzyme-linked immunosorbent assay(ELISA). RESULTS: The expression of leukocyte CD18, sICAM-1,sVCAM -1 and sC5b-9 were significantly higher in AMI patients than that in normal controls and OMI patients(P
