Expression of Fas ligand mRNA in colon cancer and its clinical significance
- VernacularTitle:Fas配体mRNA在大肠癌组织的表达及其临床意义
- Author:
Erxun DING
;
Qiang WANG
;
Kewen YUAN
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
In situ hybridization;
Ligands
- From:
Chinese Journal of General Surgery
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the expression of Fas ligand mRNA and the biological behavior and prognosis of colon cancer.Methods The expression of Fas ligand mRNA was examined in 52 cases of colon cancer by in situ hybridization (ISH) technique.Results Fas ligand mRNA expression was found in 30 out of 52 cases of colon cancer (58%). Fas ligand mRNA expression was positive in cancer tissues in 3 out of 12 cases (25%) with pericancer inflammation and in 27 out of 40 cases (68%) with no pericancer inflammation ( P
