Difference of GCIPL Thickness of Diabetes and Normal Eyes in Spectral Domain OCT.
10.3341/jkos.2014.55.10.1476
- Author:
Sang Jun PARK
1
;
Yeon Sung MOON
;
Na Rae KIM
Author Information
1. Department of Ophthalmology and Inha Vision Science Laboratory, Inha University School of Medicine, Incheon, Korea. nrkim@inha.ac.kr
- Publication Type:Original Article
- Keywords:
Diabetes mellitus (DM);
Ganglion cell-inner plexiform layer (GCIPL);
Optical coherence tomography (OCT);
Retinal nerve fiber layer (RNFL)
- MeSH:
Diabetes Mellitus;
Diabetic Retinopathy;
Ganglion Cysts;
Humans;
Nerve Fibers;
Retina;
Retinal Ganglion Cells;
Retinaldehyde;
Tomography, Optical Coherence
- From:Journal of the Korean Ophthalmological Society
2014;55(10):1476-1480
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To analyze the difference of the ganglion cell-inner plexiform layer (GCIPL) thickness in diabetic and normal eyes of patients using spectral domain optical coherence tomography (OCT) (Carl Zeiss Meditec, Dublin, CA, USA). METHODS: The authors compared and analyzed the difference of the GCIPL thickness measured with spectral domain optical coherence tomography (OCT) in 42 diabetic and 92 normal subjects. RESULTS: The study subjects were divided into 3 groups: 92 normal subjects, 22 diabetic patients without diabetic retinopathy, and 26 diabetic patients with diabetic retinopathy. Presence of diabetes mellitus (DM) or diabetic retinopathy did not influence the retinal nerve fiber layer (RNFL) thickness. The GCIPL thickness tended to be thinner especially in the superior sector GCIPL. The GCIPL thickness of normal subjects, diabetes patients without diabetic retinopathy, and diabetic retinopathy patients was 82.24 +/- 7.21 microm, 81.86 +/- 9.53 microm, and 76.77 +/- 14.13 microm, respectively, especially in the superior sector GCIPL (p = 0.029). CONCLUSIONS: Retinal ganglion cell layer thinning was induced by diabetes and diabetic retinopathy, and originated specifically from the superior part of the retina.
