Preparation of Chitosan-oxaprozin Sustained Release Tablets
- VernacularTitle:壳聚糖-恶丙嗪缓释片的研制
- Author:
Zuxiong LIU
;
Xiaodong LI
;
Ren TANG
;
Li SHENG
- Publication Type:Journal Article
- Keywords:
chitosan;
oxaprozin;
sustained release tablet;
preparation;
quality control
- From:
China Pharmacy
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study the preparation and quality standard of chitosan-oxaprozin sustained release tablets, and observe the rule of in vitro release of oxaprozin. METHODS:The content of oxaprozin in the tablets was determined by UV - spectrophotometry. RESULTS:The linear range was 2. 5- 15. 0ug/ml. The average recovery was 99. 79% with a RSD of 0. 38%. CONCLUSION: The preparation process of chitosan-oxaprozin sustained release tablet is simple. It is worth expanding the app- lication in clinical practice.