Determination of Ofloxacin Excretion in Urine by UV - spectrophotometry Method
- VernacularTitle:紫外分光光度法测定尿中氧氟沙星的排泄量
- Author:
Ting XU
;
Rongli MA
;
Ping FAN
;
Xiaoou PAN
- Publication Type:Journal Article
- Keywords:
ofloxacin;
UV-spectrophotometry;
excretion in urine
- From:
China Pharmacy
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the pharmacokinetic characteristics of domestic ofloxacin tablet. METHODS: A method of deter- mination of drug concentration in urine by UV-spectrophotometry was established. RESULTS: K = 0. 1 278/h; T1, 2 = 5. 96h, Xu0-24 = 165. 84mg; (Q) = 82. 84%. CONCLUSION: This method is simple and rapid, it is suitable for pharmacokinetics study and clinical monitoring.
