Chemoelimination-spectrophotometry for Determination of the Content of Benzalkonium Bromide in Dis- infectant Solution
- VernacularTitle:化学消除-分光光度法测定苯扎澳铵制剂含量
- Author:
Guochang LI
;
Yong YUAN
;
Yong CHEN
- Publication Type:Journal Article
- Keywords:
benzalkonium bromide. UV-spectrophotometry;
determination of content
- From:
China Pharmacy
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To establish a new method for measuring the content of benzalkonium bromide in disinfectant so- lution METHODS: The sodium nitrite was removed from disinfectant solution by reaction between sodium nitrite and urea to form N2 and CO2 and then benzalkonium bromide in the solution was directly determinated by UV-spectrophotometry with no need of separation RESULTS:There was no significant difference between this method and the method in pharmacopeia CON CLUSION:The method is simple, rapid and accurate and can be used to measure benzalkonium bromide in the solution.
