A Study on the Ratio of T_H1, T_H2 Cell in the Peripheral Blood from Patients with Severe Pregnancy Induced Hypertension
- VernacularTitle:妊娠高血压综合征患者外周血T_H1和T_H2细胞比例变化的研究
- Author:
Xiuxia WANG
;
Lixia HE
;
Lurong QU
- Publication Type:Journal Article
- Keywords:
Pregnancy complications, cardiovascular;
Hypertension;
Th1 cells;
Th2 cells;
Flow cytometry
- From:
Chinese Journal of Perinatal Medicine
1998;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the immunologic etiology of pregnancy induced hypertention (PIH)by studying the changes of T H1 and T H2 cell ratio in the peripheral blood from patients with severe PIH. Methods We examined the cell percentage of T H1 cell(secreting cytokine IFN ?) and T H2 cell(secreting cytokine IL 4),which were from CD4 positive, by flow cytometry tri stained with PerCP CD4,FITC IFN ? and PE IL 4 monoclonal antibody. The blood samples were from severe PIH patients and normal third trimester patients. Results The percentage of T H1 cell 38.01?9 04% from the peripheral blood of severe PIH partuients was significantly higher than that of the normal partuients of the third trimester 30.26?8.65%, while the percentage of T H2 cell 2.25? 0.61% was much lower P
