An ivestigation on pathogenesis of chronic hypotony following anterior proliferative vitreoretinopathy
- VernacularTitle:前部增生性玻璃体视网膜病变引起慢性低眼压发病机制的探讨
- Author:
Baichen LIU
;
Maonian ZHANG
;
Tiecheng LIU
- Publication Type:Journal Article
- Keywords:
Vitreoretinopathy,proliferative/complications;
Ocular hypotension/etiology
- From:
Chinese Journal of Ocular Fundus Diseases
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the occurrence, progress and conversion of hypotony in anterior proliferative vitreoretinopathy (aPVR), and to provide knowledge about how to prevent and treat it. Methods Animal models of chronic hypotony by aPVR were made with cultured homologous dermal fibroblasts on pigmented rabbits. The intraocular pressure (IOP) and ultrasound biomicroscopy(UBM) examination were taken preoperatively and on days 7,14, 28 and 56 postoperatively. Rabbits were killed on days 14, 28 or 56 postoperatively, prepared for histology and ultrastructure examination. Results The average IOP of experimental group was lower than that of control group on days 7,14,28 and 56 significantly (P
