Effect of Human Parvovirus B19 Infection in the Development of Aplastic Anemia
- VernacularTitle:人细小病毒B19感染在再生障碍性贫血发病中的作用
- Author:
Xinhong QIAN
;
Yuejie ZHENG
;
Guocheng ZHANG
- Publication Type:Journal Article
- Keywords:
Human parvovirus B19;
Aplastic anemia;
Nested polymerase chain reaction
- From:
Journal of Chinese Physician
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the role of human parvovirus B19(HPV B19) infection in the onset of aplastic anemia(AA).Methods The presence of HPV B19-DNA was detected in the peripheral blood samples from 22 patients with AA(aplastic anemia) by using nested polymerase chain reaction assay,and 20 healthy blood donors as control.Results Seven of 22(31 8%) AA cases were HPV B19-DNA positive,while all the samples from the control group were negative for HPV B19-DNA (P0 05).Conclusion HPV B19 infection is closely related to the onset of AA,and may be an important viral cause for AA.
