Study on Activated Protein C in Patients with Neuropsychiatric Lupus Erythematosus
- VernacularTitle:神经精神性红斑狼疮的抗活化蛋白C研究
- Author:
Xiangpei LI
;
Xiaomei LI
;
Jingsheng WU
- Publication Type:Journal Article
- Keywords:
Lupus erythematosus,systemic;
Activated protein C resistance;
Antibodies,antiphospholipid
- From:
Chinese Journal of Dermatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the significance of activated protein C resistance (APCR) and antiphospholipid antibody(APA) in patients with neuropsychiatric lupus erythematosus(NPLE). Methods APCR, anticardiolipid antibody (ACA)(IgG, M, A), lupus anticoagulant (LA) were measured with APTT? APC, ELISA, PTT－ LA methods, respectively, in 21 NPLE patients and 88 SLE patients without NPLE(NNPLE). Results The positive rates of APCR and ACA(IgG) in NPLE group were 78.9％ (15/19) and 52.4％ (11/21), respectively, which were significantly higher than those in NNPLE group: 44.3％ (39/88) and 22.7％ (20/88), respectively (P
