Expression of p27 and Cyclin D1 in Keratinocyte－ Derived Tumors
- VernacularTitle:p27、细胞周期素D_1在恶性角质形成细胞肿瘤中的表达
- Author:
Juan DU
;
Ping TU
;
Guiying LIU
- Publication Type:Journal Article
- Keywords:
Bowen′ s disease;
Carcinoma,basal cell;
Carcinoma,squamous cell;
p27;
Cyclin D1
- From:
Chinese Journal of Dermatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between expression of p27 and cyclin D1 protein in keratinocyte－ derived tumors. Methods Expression of p27 and cyclin D1 protein was determined in various keratinocyte－ derived tumors by immunohistochemistry techniques. Results Significantly higher expression of p27 was found in both Bowen′ s disease and actinic keratosis(AK) than that in basal cell carcinoma(BCC) and squamous cell carcinoma(SCC)（ P
