Preparation and Clinical Application of Compound Fleroxacin Ear-drops
- VernacularTitle:复方氟罗沙星滴耳液的制备及临床应用
- Author:
Lei ZHANG
;
Xin LI
;
Zhenjia ZHANG
;
Weihong SUN
- Publication Type:Journal Article
- Keywords:
fleroxacin;
ear-drops;
quality control
- From:
China Pharmacy
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the quality control,stability and therapeutic effect of compound fleroxacin ear-drops.ME_THODS:The content of fleroxacin in the ear-drops was determined by ultraviolet spectrophotometry.RESULTS:There was a good linearity in a range of concentrations from 2?g/ml to 12?g/ml,r=0.9 998,average rate of recovery was 100.38%,RSD=0.39%(n=6).The preparation showed stable quality and satisfactory effect.CONCLUSION:This ear-drops is simple in preparation,reliable in quality-control and effective in clinical use.