Analysis of Factors Related to and Prophylactico-therapy of Drug-induced Renal Damage
- VernacularTitle:药物性肾损害的因素分析和防治探讨
- Author:
Weiping CAI
;
Yunqiou ZHU
- Publication Type:Journal Article
- Keywords:
drug;
renal damage;
acute renal failure;
glutathione
- From:
China Pharmacy
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the pathogenic factors and prevention and cure of drug-induced renal damageMETHODS:According to the clinical manifestations,110 cases of drug-induced renal damage were divided into two types∶one type had acute renal failure(ARF),another had hematuria and proteinuria but no ARFOf 110 cases,65(32 ARF)were treated with glutathione,45(31 ARF) as controlRESULTS:Of 110 cases,49(472%)had received more than two kinds of nephrotoxic agents,72(655%) had had fever and had received antibiotics or dehydrantsThe effective rates for ARF in above-mentioned two groups were 906% and 645% respectivelyThe effective rates for hematuria and proteinuria were 848% and 572% respectively with significant difference(P
