Effects of Stimulation of Wind, Cold and Dampness on Metabolism of Oxygen Free Radical and Prostaglandin in Cervical Muscle and Blood in Rabbits
- VernacularTitle:风寒湿刺激对家兔颈部肌肉及血液组织中氧自由基和前列腺素代谢的影响
- Author:
Jie JIANG
;
Qi SHI
- Publication Type:Journal Article
- Keywords:
Free radicals/metabolism, prostaglandins/ metabolism, cervical spondylopathy/metabolism
- From:
Journal of Traditional Chinese Medicine
1992;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
In order to probe into effect of stimulation of wind, cold and Sdampness to the cervical part on oxygen free radical and prostaglandins, 24 rabbits were randomly assigned to control group and wind - cold - Sdampness group, head - lowering group and combined model group, 6 rabbits in each group, and changes of superoxide dismutase (SOD),lipid hyperoxide (LPO), prostanglandin E2 (PGE2), 6 -keto -PGF1a in affected local region and blood were observed. Results indicated that the commonly - seen pathogenetic factors of cervical spondylopathy such as wind, cold , dampness and lowering head might cause aspetic inflammation of the cervical part and abnormality of SOD, LPO, PGE2 and 6 - keto - PGF1a in affected local tissue and blood, and abnormal metabolism of oxygen free radical and prostagnadins might be one of important mechanisms of cervical spondylopathy induced by wind, cold and dampness.
