Tubulin expression of basal cells in patients with Alzheimer's disease and vascular dementia
- VernacularTitle:阿尔茨海默病与血管性痴呆基底细胞微管蛋白变化研究
- Author:
Jihua XIAO
;
Chaoyong XIA
;
Yanbin JIA
;
Pei ZHENG
- Publication Type:Journal Article
- Keywords:
Alzheimer disease;
Cells;
Tubulin;
Diagnosis
- From:
Chinese Journal of Pathophysiology
2000;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate quantitatively the tubulin expression of basal cells in patients with Alzheimer's disease(AD) and vascular dementia(VD) and evaluate its significance in diagnosing Alzheimer's disease. METHODS: ?-tubulin of basal cells was examined using LSAB immunohistochemical technique, and analyzed qualitatively and quantitatively by image analyzer. RESULTS: The integrated absorbance (I A ,261.43?25.21) and the average absorbance (A A ,1.89?0.14) in the AD group were significantly higher than those (I A ,120.55?19.71 and A A , 0.85?0.14, respectively)in the VD group ( P
