The Expression of Hyaluronan Synthase mRNA in the Endolymphatic Sac Cells and Renal Tubules
- VernacularTitle:内淋巴囊和肾小管上皮细胞透明质酸合成酶mRNA的表达
- Author:
Zhonglin MOU
;
Zhaohua LIU
;
Jian CHEN
- Publication Type:Journal Article
- Keywords:
Endolymphatic sac Renal tubules Hyaluronan synthase In situ hybridization
- From:
Journal of Audiology and Speech Pathology
1998;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the difference between the mRNA expressions of hyaluronan synthase in the epithelial cells of endolymphatic sac and renal tubules with the oligonucleotide probe. Methods The oligonucleotide probe of hyaluronan synthase was designed and synthesized, the mRNA expressions of hyaluronan synthase in the epithelial cells of endolymphatic sac and renal tubules were detected with hybridization in situ. Results mRNA of hyaluronan synthases were strongly expressed in some epithelial cells of endolymphatic sac and renal tubules. Conclusion It is confirmed that a dual regulatory system for hyaluronan /hyaluronidase exists in the epithelial cells of endolymphatic sac and renal tubules at the level of molecular biology.
