Intracellular Cytokine Detection in Peripheral Blood CD3~＋ T Cells of Patients with Recurrent Genital Herpes
- VernacularTitle:复发性生殖器疱疹患者外周血CD3~+T细胞内细胞因子的检测
- Author:
Qifeng QIAN
;
Hongwei GUO
- Publication Type:Journal Article
- Keywords:
Herpes genitalis;
Cytokines;
Flow cytometry
- From:
Chinese Journal of Dermatology
1995;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the role of Th1/Th2 cytokine profile in the pathogenesis of recurrent genital herpes (RGH), and to find out the relationship between Th1/Th2 cytokines. Methods A two-colour immunofluorescent staining of cell surface antigen and intracellular cytokines (IL-2、 IL-10、 IL-12、 IFN－? and TNF－? ) in CD3＋ T-lymphocytes of 20 patients with RGH with flow cytometric analysis were performed. Results Compared to controls, patients with RGH showed a decreased number of CD3＋ T cells（ P0.05） . Conclusions RGH patients seem to have a predominance of Th2 cytokine profile, which may play an important role in the pathogenesis of RGH.
