The detection of CEA mRNA in gallbladder bile of patients with colorectal cancer and its clinical significance
- VernacularTitle:胆囊胆汁中CEAmRNA的表达与大肠癌肝转移关系的研究
- Author:
Shiyong LI
;
Chengyu LUO
;
Ping AN
- Publication Type:Journal Article
- Keywords:
Bile;
Neoplasm metastasis;
Intestine, large
- From:
Chinese Journal of General Surgery
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical significance of CEA mRNA expression in gallbladder bile for early diagnosis of liver metastasis from primary colorectal cancer. Methods [WT5”BZ] A CEA specific nest RT PCR assay was used to detect CEA mRNA expression in the gallbladder bile of 46 patients with colorectal cancer. Results The positive rate of CEA mRNA in gallbladder bile was 74%. The rate was directly proportional to that of live metastasis. Liver metastasis developed in 33% of patients with positive CEA mRNA expression. Conclusions The positive expression of CEA mRNA in gallbladder bile is a proof of prospective liver metastasis.
