Postoperative changes of serum proteins and immune response in critical patients and the effects of recombinant human growth hormone
- VernacularTitle:危重患者术后血浆蛋白和免疫功能的变化及重组人生长激素的治疗作用
- Author:
Fushun WANG
;
Xi ZHU
;
Xisheng LENG
- Publication Type:Journal Article
- Keywords:
Critical illness;
Hypoproteinemia;
Immunosuppression;
Somatotropin
- From:
Chinese Journal of General Surgery
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the postoperative changes of serum proteins and immune responses in critical patients and the effect of recombinant human growth hormone(rhGH).Method 45 critical patients were divided randomly into rhGH group (15 cases) and control group (30 cases) after operation. Patients in rhGH group were given rhGH 8*!U/d,im for 7 days starting 48 hours post operation. Result The postoperative level of serum transferin,albumin and prealbumin decreased in all patients, and so did the activity of CD 3,CD 4 ,CD 8,NK and the ratio of CD 4/CD 8 .Serum prealbumin level increased significantly in rhGH group at day 4 and after ( P