The expression of mitogen-activated protein kinase and its upstream regulated signal in human hepatocellular carcinoma
- VernacularTitle:有丝分裂蛋白激酶及其上游调节信号在人肝癌组织中的表达
- Author:
Guangming LI
;
Jiye ZHU
;
Yannan LIU
- Publication Type:Journal Article
- Keywords:
Carcinoma, hepatocellular;
Ca 2+ calmodulin dependent protein kinase;
Growth substances
- From:
Chinese Journal of General Surgery
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective This study was to detect protein expression of ERK 1,ERK 2,JNK 1,p38 and MEK 1 ,MEK 2 in human hepatocellular carcinoma and adjacent non neoplastic liver tissues.Method Western blot was used to detect the expression of ERK 1,ERK 2, JNK 1,p38 and MEK 1,MEK 2 in the surgically resected hepatocellular carcinoma and para carcinoma tissues in 16 HCC patients.[WT5”HZ] Result The expression of ERK 1,ERK 2,p38 expressed by integral optic density (IOD) in hepatocellular carcinoma was significantly higher than that in para carcinoma respectively: as for ERK 1 it was 300?98 in carcinoma and 98?48 in para carcinoma tissues ( P
