Study on the expression of nitric oxide synthase 1(NOS1)and mRNA after rat cerebral contusion
- VernacularTitle:大鼠脑挫伤后神经元一氧化氮合成酶表达的研究
- Author:
Long CHEN
;
Zhong LI
;
Yunju GU
- Publication Type:Journal Article
- Keywords:
Cerebral contusion;
Timing of injury;
NOS1;
Immunohistochemistry;
In situ hybridization
- From:
Chinese Journal of Forensic Medicine
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The experimental right cerebral contusion model was established in rats.To observe the relationship between the expression of Nitric oxide synthase 1(NOS1)and time elapsed after cerebral contusion,the expression of Nitric oxide synthase 1(NOS1)and mRNA was studied by immunohistochemistry and in situ hybridization at different intervals after cerebral injury.The results indicated that a positive relationship existed between the expression of NOS1 and NOS1 mRNA and the intervals elapsed after brain injury.This method also can be used to distinguish antemortem and postmortem injury rat′s cerebral contusion.So that,the expression of NOS1 and NOS1 mRNA is of great value for timing of brain injury.
