Study on the relationship between the postmortem interval and the changes of DNA content in the rat's brain cells by the computerized image analysis
- VernacularTitle:大鼠脑细胞DNA含量与死亡时间关系的图像分析
- Author:
Liang LIU
;
Dongbing PENG
;
Weinian DENG
- Publication Type:Journal Article
- Keywords:
Postmortem interval;
Image analysis;
Rat;
DNA degradation
- From:
Chinese Journal of Forensic Medicine
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Estimation the postmortem interval(PMI)is an important subject in forensic medicine practice.Recent research has found that the DNA molecular would degrade immediately following death,and the quantity of DNA in nuclear would be decreasing along with the elapse of the time since death.Seven parameter of cell nuclear,including the area and integral optical density,were chosen and the changes of DNA content in the brain cells of 15 rats were determined at every one hour during 48 horus after death by the auto TV imange analyses system.The results showed that the degradation rate of DNA in nuclear has a certainty relationship with early PMI in rats and indicated that the determination of the quantity of DNA in nuclear is the major method to estimate the PMI.
