Anti-thrombotic,Choleretic and Anti-ulcerous Actions of Rhizoma Ligustici
- VernacularTitle:藁本的抗血栓形成、利胆和抗溃疡作用
- Author:
Mingfa ZHANG
;
Yaqin SHEN
- Publication Type:Journal Article
- Keywords:
Rhizoma Ligustici;
anti-thrombotics;
choleretics;
anti-ulcerative agents
- From:
China Pharmacy
1991;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the anti-thrombotic,choleretic and anti-ulcerous actions of Rhizoma Ligustici METHO_DS:Experiments were carried out on conventional models of choleresis and ulceration,and on a thrombotic model of using direct current continuously to stimulate the unilateral carotid artery of anesthetic rat RESULTS:Alcoholic extract of Rhizoma Ligustici 3g herb/kg and 10g herb/kg id or ig,increased choleresis and prolonged the time for arterial thrombosis induced by electric stimulation in rats,but did not prolonged coagulative time,PT and KPTT The extract 5g herb/kg and 15g herb/kg ig,inhibited the formation of gastric ulcers induced by water immersion,stress,HCl and indomethacin-alcohol in mice CONCLU_SION:Rhizoma Ligustici has anti-thrombotic choleretic and anti-ulcerous actions
